In the majority of cases, no special tests are needed to make the diagnosis of vitiligo, however in some cases, such as early vitiligo, the signs are subtle, and a skin biopsy may help. In cases where an infection such as a fungus or yeast is involved, a simple skin scarping may help.
Vitiligo can be associated with other autoimmune skin conditions, such as diabetes, thyroid disease and lupus. Blood tests can detect any associated conditions, including any vitamin deficiencies. The majority of these conditions can be managed with appropriate medical treatment.